Application

Research CategoryApoptosis & Cancer

Research Sub CategoryBCL2 & Inhibition

Immunoblot 1:2,000

Immunoprecipitation. Precipitates a 37-39 kDa protein, which appears as a doublet in some cells.

Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

The following tissues/cells can serve as positive controls: tonsil, tonsillar B cells, B-cell lines Reh, Daudi, and Karpas 422.

Optimal working dilutions for AB2910 must be determined by end user.

This Anti-Mcl-1 Antibody is validated for use in IP, WB, IH(P) for the detection of Mcl-1.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Synthetic peptide corresponding to amino acids 121-139 of human Mcl-1.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Physical form

Liquid antiserum.

Specificity

Recognizes Human Mcl-1. Not reactive with other members of the Bcl-2 family, as verified by immunoblot.

Storage and Stability

Store at -20°C for up to 12 months in undiluted aliquots. Avoid repeated freeze-thaw cycles.